(University of Tokyo) In a recent study in mice, researchers found a way to deliver specific drugs to parts of the body that are exceptionally difficult to access. Their Y-shaped block catiomer (YBC) binds with certain therapeutic materials forming a package 18 nanometers wide. The package is less than one-fifth the size of those produced in previous studies, so can pass through much smaller gaps. This allows YBCs to slip through tight barriers in cancers of the brain or pancreas.
(International Cytokine & Interferon Society) The International Cytokine & Interferon Society (ICIS) announced today that the Seymour and Vivian Milstein Award for Excellence in Cytokine and Interferon Research (The 'Milstein Award') has been bestowed on two world leaders in deciphering the fundamental mechanisms of innate immunity in directing cytokine driven responses. Akiko Iwasaki, Ph.D., and Hao Wu, Ph.D., will share the 2019 Milstein Award at the 31st Milstein Award ceremony on October 20 at Cytokines 2019, in Vienna, Austria.
(Queensland University of Technology) Researchers in Australia at Queensland University of Technology (QUT) and QIMR Berghofer Medical Research Institute have found that the dengue fever mosquito common to north and central Queensland poses the greatest danger of spreading the Zika virus in Australia.The researchers showed that not only was the dengue mosquito effective at transmitting Zika, the virus was also in the mosquitoes' reproductive organs. This finding suggests that Zika could persist in mosquito populations by females passing it to their offspring.
(University of Arizona Health Sciences) World-renowned neurobiologists and leaders in chemistry will discuss the brain circuits underlying acute and chronic pain, reward, motivation and addiction, as well as the development of chemical probes as potential novel therapies. The symposium is co-sponsored by the University of Arizona College of Medicine - Tucson Department of Pharmacology and Interim Dean Irving Kron, M.D.
(Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences ) Recently, researchers at the Caltech Optical Imaging Laboratory, directed by Lihong Wang, developed a technique for in vivo super-resolution PACT. It breaks the acoustic diffraction limit by localizing the centers of single dyed droplets flowing in blood vessels. This technique resolves brain blood vessels at a six-fold finer resolution. The research has been published in Light: Science and Applications.
(University of Michigan) The benefits of self-driving cars will likely induce vehicle owners to drive more, and those extra miles could partially or completely offset the potential energy-saving benefits that automation may provide, according to a new University of Michigan study.
(University of Illinois at Urbana-Champaign) Oxidants found within living organisms are byproducts of metabolism and are essential to wound-healing and immunity. However, when their concentrations become too high, inflammation and tissue damage can occur. University of Illinois engineers have developed and tested a new drug-delivery system that senses high oxidant levels and responds by administering just the right amount of antioxidant to restore this delicate balance.
(University of Texas at San Antonio) Four University of Texas at San Antonio (UTSA) researchers have each been awarded a National Science Foundation (NSF) Faculty Early Career Development (CAREER) Award, totaling $2 million in new research funding for San Antonio's largest public research university. CAREER Awards, one of the NSF's most prestigious programs, helps UTSA advance closer to National Research University Fund (NRUF) eligibility.
(Rockefeller University) Using new imaging technology, researchers can now record the activity of large populations of brain cells with unprecedented speed, and at new depths.
(Portland State University) Portland State University researcher Nirupama Bulusu wants to prevent counterfeit pharmaceuticals from flooding the market. Bulusu recently published a blockchain protocol that could do just that.
(Santa Fe Institute) Physicists at the Santa Fe Institute and MIT have shown that Markov processes, widely used to model complex systems, must unfold over a larger space than previously assumed.
(American Physical Society) After watching YouTube videos of people supercooling water in a bottle and then triggering it to freeze by banging it, something about this concept solidified for Matthew M. Szydagis, especially when he saw it again during the Disney movie 'Frozen.' During the 2019 American Physical Society April Meeting in Denver, Szydagis will describe how this inspired him to explore whether a subatomic particle like dark matter can trigger the freezing of supercooled water.
(Ehime University) The composition of mixed brominated/chlorinated dibenzofurans (PXDFs) and diphenyl ethers in soils from an e-waste site in Ghana suggests a formation of PXDFs through condensation of the flame retardant PBDEs and subsequent bromine-to-chlorine exchange. PXDFs were substantial contributors of toxic equivalents among dioxins from e-waste burning.
(Duke University) Biomedical engineers at Duke University have developed an automated process that can track and map active neurons as accurately as a human can, but in a fraction of the time. This new technique, based on a deep learning algorithm, addresses a critical roadblock in neuron analysis, allowing researchers to rapidly gather and process neuronal signals for real-time behavioral studies.